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Professor James D. Litster
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Contact:
Sir Robert Hadfield Building, Mappin St, Sheffield, S1 3JD +44 (0)114 222 7557 james.litster@sheffield.ac.uk |
Biography
I was previously Professor of Chemical Engineering and Professor of Industrial and Physical Pharmacy at Purdue University, Indiana, for over eight years. Prior to this, I was an academic at The University of Queensland, Australia, as well as the Head of Chemical Engineering and the Head of School of Engineering. In 2010, I was elected a Fellow of the Australian Academy of Technological Sciences and Engineering. I was awarded the Thomas Barron Award in Fluid-Particle Systems from the American Institute of Chemical Engineers in 2012, and Pharmaceutical Section Award for contributions to Quality by Design by the American Institute of Chemical Engineers.
Research
My research area is Particulate Products and Processes. My expertise is on wet granulation with over 30 years experience in the field. My key contributions include the development of key regime maps for granulation processes and the development of mathematical models for engineering design and scaling of granulation processes. I'm the co-author of the well known monograph in this area - The Science and Engineering of Granulation Processes and my approaches are now widely used in engineering practice in industry.
Predicting the structure of complex particulate products and their performance in use is a grand challenge in engineering science. The products include pharmaceuticals and consumer products, amongst others. The performance of these products is controlled by their size, structure and surface properties, as well as their chemistry. Therefore, modelling the development of these attributes must address structure at many length scales from nano-metre to micro-metre. My programme focuses on developing new design models to substantially improve the manufacture of these particulate products.
Selected Publications
I was previously Professor of Chemical Engineering and Professor of Industrial and Physical Pharmacy at Purdue University, Indiana, for over eight years. Prior to this, I was an academic at The University of Queensland, Australia, as well as the Head of Chemical Engineering and the Head of School of Engineering. In 2010, I was elected a Fellow of the Australian Academy of Technological Sciences and Engineering. I was awarded the Thomas Barron Award in Fluid-Particle Systems from the American Institute of Chemical Engineers in 2012, and Pharmaceutical Section Award for contributions to Quality by Design by the American Institute of Chemical Engineers.
Research
My research area is Particulate Products and Processes. My expertise is on wet granulation with over 30 years experience in the field. My key contributions include the development of key regime maps for granulation processes and the development of mathematical models for engineering design and scaling of granulation processes. I'm the co-author of the well known monograph in this area - The Science and Engineering of Granulation Processes and my approaches are now widely used in engineering practice in industry.
Predicting the structure of complex particulate products and their performance in use is a grand challenge in engineering science. The products include pharmaceuticals and consumer products, amongst others. The performance of these products is controlled by their size, structure and surface properties, as well as their chemistry. Therefore, modelling the development of these attributes must address structure at many length scales from nano-metre to micro-metre. My programme focuses on developing new design models to substantially improve the manufacture of these particulate products.
Selected Publications
- Pitt, K., Peña, R., Tew, J.D., Pal, K., Smith, R., Nagy, Z.K., Litster, J.D. (2018). Particle design via spherical agglomeration: A critical review of controlling parameters, rate processes and modelling. Powder Technology. 326, 327-343.
- Rashid A., White E.T., Howes T., Litster J.D., & Marziano I. (2015). The Metastability and Nucleation Thresholds of Ibuprofen in Ethanol and Water-Ethanol Mixtures. International Journal of Chemical Engineering, Article ID 560930.
- Sayin R., El Hagrasy A.S., & Litster J.D. (2015). Distributive mixing elements: Towards improved granule attributes from a twin screw granulation process. Chemical Engineering Science, 125, 165-175.
- Hapgood K., Litster J.D. & Wang C-H. (2015). Pharmaceutical particles. Chemical Engineering Science, 125, 1-3.
- Mitra B., Hilden J., & Litster J.D. (2015). Novel use of monodisperse granules to deconvolute impacts of granule size versus granule solid fraction on tablet tensile strength. Advanced Powder Technology, 26(2), 553-562.
- Lu J., Litster J.D. & Nagy Z.K. (2015). Nucleation Studies of Active Pharmaceutical Ingredients in an Air-Segmented Microfluidic Drop-Based Crystallizer. Crystal Growth & Design, 15(8), 3645-3651.